Dr. M. J. Bosma and his colleagues at the Fox Chase Cancer Center found mutant mice that have symptoms similar to human severe combined immunodeficiency among C.B-17/lcr mice from a congenic strain of BALB/cAn with a different Igh gene locus.
Because the characteristics are under the control of a single recessive gene, the gene was named scid.
Characteristic
T cells and B cells present, but there is hardly any immune reaction in vivo
유전모드: scid, Chromosome 16 single recessive gene
Lack functional T cells and B cells, there is hardly any production of immunoglobulin in addition to the absence of cell immunity.
These mice present with symptoms similar to those of human severe combined immunodeficiency.
Immunoglobulin Production: Generally not produced (but Leaky (lg+) animals present, accounting for several percent)
새론바이오는 일본 CLEA의 CB17-Scid (스키드 마우스)를 공급합니다. 
CB17-Scid 마우스
